Travel around the globe and meet extraordinary individuals who suffer from conditions so rare and mysterious that the medical world is often baffled.

Tammy's weight loss surgery doesn't go as expected. Meanwhile, Amy meets with Dr. Procter and gets an ambitious weight loss goal.

Follows the journeys of the fence pole embedded in an American trucker's midriff to the sewing needle which an elderly man accidentally eats as part of his dinner.

Renowned anaplastologist Allison Vest creates life-changing prosthetics. She helps a man who lost his nose and a cancer survivor seeking new nipples.

It's birthday season in the Busby house! As the Quints turn four, the girls say goodbye to night-time diapers. And, Adam's new job means major stress for Danielle.

Girly bride Evie always dreamed of a pink princess dress, but her top choice is twice her budget. And, Gok helps a police officer bride visualise her gown.

Today Buddy cooks up his seaside favourites for his two favourite Frankies - his uncle and cousin. On the menu is blue fish, linguini and clams and sea robin soup.

Darcey and Jesse's dispute spirals. Larry questions Jenny's past on his first day in Manila. Patrick must make a big decision in Paris after Myriam's bombshell.

Sean meets Abby's ex in an emotional showdown. Jesse and Darcey hit breaking point. Paul reveals a big secret to Karine, leading to a dangerous encounter in Brazil.

Truth Or Dare. Jonah and his friend Bryant enter their first BBQ competition. Alex confides in Jonah that his relationship with Allie is causing him stress.

One of the best football clubs in the world, F.C Internazionale Milano, made it to Hoboken! Buddy is excited and wants to welcome them with a beautiful cake.

Buddy creates a fire-breathing dragon cake for a medieval knight. Plus, a cat café wants Mary to bake for a feline wedding - and to officiate it!

Buddy, his wife and his sister, go south of the border. This Mexican fiesta includes fajitas with tomato salsa, quesadillas and churros with chili chocolate sauce.

Adam gets an exciting new job opportunity, but he needs the quints' help. Meanwhile, Parker struggles with her anxiety again and Blayke takes up a new hobby.

Even a massive snowstorm can't keep the diehard pageant kids away! Birthday girl Roni, 3, surprises the audience and impresses the judges with her performance.

Darcey and Jesse's dispute spirals. Larry questions Jenny's past on his first day in Manila. Patrick must make a big decision in Paris after Myriam's bombshell.

Sean meets Abby's ex in an emotional showdown. Jesse and Darcey hit breaking point. Paul reveals a big secret to Karine, leading to a dangerous encounter in Brazil.

Mee Wei isn't afraid to flaunt her curves, but most bridal boutiques do not carry dresses in her size. Ellice is worried her dress might be too sexy.

Princess-to-be Puteri wants a dress fit for her royal wedding in South Africa. Cynthia struggles to trust her instincts in choosing her dream dress.

Cher and Dawn are officially triplets after the baby's arrival! And, Mary's shocking graduation gift to Brittani turns heads at her graduation party.

One of the best football clubs in the world, F.C Internazionale Milano, made it to Hoboken! Buddy is excited and wants to welcome them with a beautiful cake.

Buddy creates a fire-breathing dragon cake for a medieval knight. Plus, a cat café wants Mary to bake for a feline wedding - and to officiate it!

The Browns reach the home of another polygamist family. They are shocked to discover that the other family operate on discipline and rigidity.

Adam and Danielle want the girls eating healthier, but the Quints aren't on board. The Busby's get surprising news about their house, forcing a big decision.

Single mum Rachel prepares to travel to England with a baby. Grandmother Angela gets ready to meet her Nigerian prince. And, Darcey welcomes Jesse to America.

1950s-mad bride Danielle wants a vintage-style dress, but will it be within her budget? Two brides help each other find their dream dresses.

Buddy's sister stops by to show off her meatloaf, while he adds mashed potatoes and mac n' cheese. And for a perfect ending to the day, dig in to apple crisp à la mode.

Carlo's team takes a cake order for delivery to all the way to Saudi Arabia. Back home a fight is brewing over the bakery's signature pastry.

Buddy gets a visit from Leah, a seven-year-old baker he met in Malaysia. Mauro and Madeline help a young man propose to his sweetheart.

Despite having his second surgery cancelled and losing his home, David is determined to stay strong. Syreeta suffers a devastating personal tragedy.

Despite having his second surgery cancelled and losing his home, David is determined to stay strong. Syreeta suffers a devastating personal tragedy.

Amy wears a mask of makeup to hide the angry red blotches on her face. Dr Emma races to remove a tricky lipoma before the anaesthetic wears off.

Jelani has a skin condition that has left him with painful lumps and unsightly scars. Monique seeks treatment for a strange lump at the end of her nose.

In Sweden, Kim has had dozens of surgeries on a huge facial tumour but stopped after a near death experience. Now he needs one more operation but can he go through with it?